Paricalcitol Inhibits Renal Inflammation by Promoting Vitamin D Receptor–Mediated Sequestration of NF-κB Signaling
نویسندگان
چکیده
منابع مشابه
Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling.
Inflammation is a pathologic feature of a variety of chronic kidney diseases. Several lines of evidence suggest a potential anti-inflammatory role for vitamin D in chronic kidney disease, but the underlying mechanism remains unknown. Here, the effect of the synthetic vitamin D analogue paricalcitol on renal inflammation was investigated in a mouse model of obstructive nephropathy. Paricalcitol ...
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Vitamin D deficiency is associated with an increased risk of cardiovascular disease, diabetes, colon and breast cancer, infectious diseases and allergies. Vascular alterations are an important pathophysiological mechanism of sepsis. Experimental data suggest that paricalcitol, a vitamin D2 analogue, exerts beneficial effects on renal inflammation and fibrosis. In the present study, we aimed to ...
متن کاملAuthor's response to reviews Title: Paricalcitol Reduces Oxidative Stress and Inflammation in Hemodialysis Patients Authors:
SU424. World Congress of Nephrology 2011. Vancouver, Canada.48. Tan X, Wen X, Liu Y: Paricalcitol inhibits renal inflammation by promotingvitamin D receptor-mediated sequestration of NF-kappaB signaling. J AmSoc Nephrol 2008, 19(9):1741-1752. 49. Gamboa JL, Pretorius M, Todd-Tzanetos DR, Luther JM, Yu C, Ikizler TA,Brown NJ. Comparative effects of angiotensin-converting enzyme
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2008
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2007060666